Leukoplakia is an overgrowth of cells that results in a rough patch of whitish tissue. It can develop anywhere in your mouth. These patches typically are not painful and are not contagious. They can result from irritations such as ill-fitting dentures or the habit of chewing on the inside of the cheek. Leukoplakia also occurs among tobacco users. Treatment begins with the identifying the source of the irritation. Once the irritant is removed—which may mean giving up tobacco—the patches should disappear. Sometimes, leukoplakia is associated with oral cancer, so it’s important to maintain regular check-ups if you notice any of these patches developing. We may recommend a biopsy if the patch appears suspicious.